Propylene glycol is used:
- As an ingredient in the oil dispersant Corexit, used in great quantities during the Deepwater Horizon oil spill. As a solvent in many pharmaceuticals, including oral, injectable and topical formulations (notably, diazepam, which is insoluble in water, uses propylene glycol as its solvent in its clinical, injectable form)
- As a humectant food additive, labeled as E number E1520
- As an emulsification agent in Angostura and orange bitters
- As a moisturizer in medicines, cosmetics, food, toothpaste, shampoo, mouth wash, hair care and tobacco products
- As a carrier in fragrance oil
- To produce polyester compounds
- As a base in deicing solution
- As an ingredient in massage oils
- In hand sanitizers, antibacterial lotions, and saline solutions
- In smoke machines to make artificial smoke for use in firefighters' training and theatrical productions
- In electronic cigarettes, as a vaporizable base for diluting the nicotine liquid
- As a solvent for food colors and flavorings
- As an ingredient, along with wax and gelatin, in the production of paintballs
- As a moisture stabilizer (humectant) for snus (Swedish style snuff)
- As a cooling agent for beer and wine glycol jacketed fermentation tanks
- As a nontoxic antifreeze for winterizing drinking water systems (for example recreational vehicles), and in applications where the used antifreeze eventually will be drained into the soil, water, or a septic system
- As a less-toxic antifreeze in solar water heating systems
- As a solvent used in mixing photographic chemicals, such as film developers
- In cryonics
- As a working fluid in hydraulic presses
- As a coolant in liquid cooling systems
- To regulate humidity in a cigar humidor
- As the killing and preserving agent in pitfall traps, usually used to capture ground beetles
- As an additive to pipe tobacco to prevent dehydration
- To treat livestock ketosis
- As the main ingredient in deodorant sticks
- To deice aircraft
- As an ingredient in UV or blacklight tattoo ink
- As a lubricant in air conditioning compressors
- As a wetting agent, used to determine drying time in paints and coatings
- Used in the beverage mixer Sweet N Sour.
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